Yes, if it covers an opening or route required by that installation. The correct ventilation arrangement must be checked against the model's installation instructions.
What the observation tells you
A plinth can look neatly fitted while preventing the designed airflow. The problem may become noticeable after kitchen decoration or storage changes. Drilling random holes is not a reliable substitute for the specified opening size and path.
A useful next step
Remove loose items from existing accessible vents, but leave structural alterations to a competent installer. Tell the repair team about recent cabinetry changes and whether the fridge is integrated so they can assess both access and operating conditions.
Manuals and supporting guidance
Model-specific instructions take priority. These references support the practical principles discussed here; they do not diagnose your appliance.